According to [71], the proximal 22q11.2 deletion region shared by individuals developing PD contains plausible candidate genes, such as microRNA miR-185, predicted to target LRRK2 [80] and DiGeorge Critical Region 8 (DGCR8), a key gene in the biogenesis of brain microRNA [81]. Here, LRRK2 is linked to Parkinson disease.