The plasma IAPP levels in Cohort II did not differ significantly between +Aβ and −Aβ cases (Table S8) or between APOE4 carriers and non-carriers (253.37 ± 34.81 vs. 244.29 ± 18.66, respectively, p = 0.914), regardless of controlling for T2D (p = 0.390 and p = 0.436, respectively). Here, APOE is linked to type 2 diabetes mellitus.