Dysregulation of those pathways is related to cancer etiopathology, so in addition to the well-known role of nAR in prostate cancer [53], nAR’s connection with breast [54], bladder [55], hepatocellular [56], ovarian [57], endometrial [58], uterine [59], and many other tumor types [60] is also known. Here, CPSF4 is linked to Familial prostate cancer.