Although CCSK is apparently a genetically stable tumor, two mutually exclusive genetic events have been systematically reported: different BCOR gene ITDs on the exon 16 in more than 80% of cases [13,14,15,16,17] and the t (10;17) involving the YWHAE-NUTM2 fusion in up to 12% of cases [13,14,15,16,17,18,19,20]. Here, BCOR is linked to neoplasm.