A prospective study observed that urinary albumin excretion decreased significantly (from 127.05 ± 84.79 to 104.81 ± 74.05 μg/mg) in patients with type I DM with microalbuminuria with vitamin D deficiency after oral administration of 0.25 μg calcitriol per day for 6 months [96]. The gene discussed is ALB; the disease is vitamin D deficiency.