In SCLC, MUC1-C activates the MYC pathway in classic NE SCLC-ASCL1 (SCLC-A), variant NE SCLC-NEUROD1 (SCLC-N) and non-NE SCLC-POU2F3 (SCLC-P) subtypes (Table 1) [100]. This evidence concerns the gene POU2F3 and small cell lung carcinoma.