As regards the genetic background of hypertension, MMP-9-1562C/T polymorphism was reported as an independent predictor of arterial hypertension on the basis of the observation, that in treatment-naïve, hypertensive T-allele carriers, the values of both systolic as diastolic BP, carotid-femoral PWV and serum MMP-9 concentrations were significantly higher than in CC-homozygotes [84]. This evidence concerns the gene MMP9 and Hypertension.