Authors of another study demonstrated different plasma MMPs profiles in patients with hypertension complicated by LVH in comparison with patients suffering from DHF, apart from elevated levels of MMP-2 and MMP-9 in hypertensive patients with cardiovascular remodeling, with the significantly increased concentrations of MMP-3 and -7 and a decreased level of MMP-8 in the latter group of patients [87]. This evidence concerns the gene MMP2 and Dengue hemorrhagic fever.