Results found that depletion of RRP15 increased E-cadherin and decreased N-cadherin expressions, whereas RRP15 overexpression decreased E-cadherin and increased N-cadherin expressions in CC cells, highlighting that RRP15 regulated tumor invasion through modulation of EMT in CC, confirming the clinical potential of RRP15 as a target for EMT suppression in CC. The gene discussed is RRP15; the disease is neoplasm.