Such hybrid AuNPs, coated with water-soluble chitosan (WSCS) and [Lys1-Lys3(DOTA)]bombesin (DOTA-BBN), were prepared by Tangthong et al. to target GRPR-overexpressing PC-3 and LNCaP prostate cancer cells selectively [81]. The gene discussed is GRPR; the disease is Familial prostate cancer.