TP53 and hepatocellular carcinoma: A WES analysis of tumoral and peritumoral tissues collected from 100 Chinese HCC patients and 175 HCC patients from the TCGA revealed that HBV-related HCC had a low immune cell infiltration and TP53 mutation, but TMB was not associated with immune infiltration in HBV- and alcoholic-related HCC patients of the TCGA cohort [78].