SDCBP and cancer: MDA-9 is involved in multiple signaling pathways that involve FAK, PIP2, c-Src, p38, MAPK, NF-κB, AKT, SP1, IGFBP2, SPRR1B, and EGFR [13,26,27,28,29], and has been demonstrated to drive the invasion and migration of cancer cells, e.g., small cell lung cancer [30].