However, PGC-1α expression was increased in blood cells at 72 h and this induction was positively correlated with the infarct size and cardiac remodeling [123], so the authors finally suggested that increase of PGC-1α expression can be part of the recovery response of the mitochondrial protection system to MI, and could be an index of cardiac recovery [124]. The gene discussed is PPARGC1A; the disease is myocardial infarction.