Moreover, knockdown and restraint of RPS5 overexpression can increase the progression of hepatic fibrosis induced by dimethylnitrosamine (DMN) or bile duct ligation (BDL), which is associated with the modulation of Akt phosphorylation and HSC number in the fibrotic liver [20] for sequenced cDNA of 715 bp (RPS5) from a murine erythroleukemia (MEL) cDNA library. This evidence concerns the gene RPS5 and Hepatic fibrosis.