Mutations in the genes golgin b1 (golgb1) and activin A receptor, type 1 like (acvr1l) have been associated with the development of hyperphosphatemic familial tumoral calcinosis (HFTC) [37] and fibrodysplasia ossificans progressiva (FOP) [39]—rare disorders associated with the development of ectopic calcification [61,62]. The gene discussed is ACVRL1; the disease is fibrodysplasia ossificans progressiva.