TGFB1 and pachyonychia congenita: Considering the possible role of PC in the pathogenesis of AITD [36] and the association of these structures with EMT [40,41], we performed a morphometric analysis of PC in serum-starved NThy-ORi 3.1 cultured cells at 24, 48, and 72 h after EMT induction by TGF-β.