In the multinational SABRUS (Survey on Arrhythmic Events in Brugada Syndrome) research, VF inducibility throughout PVS was linked with a comparable time to the onset of the first arrhythmic episode as individuals with an SCN5A mutation and a family history of SCD, but longer compared to those with spontaneous type 1 ECG or syncope [201]. This evidence concerns the gene SCN5A and Brugada syndrome.