These are formed by amyloid-beta (Aβ) in Alzheimer’s disease (AD), tau in AD and other tauopathies such as frontotemporal dementia, α-synuclein (α-Syn) in Parkinson’s disease (PD), Lewy bodies (LBs) in Lewy body dementia, and pri on proteins in prion diseases such as Creutzfeldt–Jakob disease, among others [3]. The gene discussed is MAPT; the disease is Alzheimer disease.