Wen et al. [68], using data from 220 ESCC patients in a retrospective study, assessed the potential value of classifying patients according to PD-L1 and CD8+TIL expression levels with CT-based radiomics and suggested that predictive performance can be significantly increased by a combination of clinical factors and radiomics signatures. The gene discussed is CD8A; the disease is esophageal squamous cell carcinoma.