IRF1 and posterior uveitis: Review of the activity of these transcription factors, as reported in the published literature, identified five candidates with the potential to induce expression of human retinal endothelial cell ICAM-1, a central cell adhesion molecule coordinating leukocyte interactions in non-infectious posterior uveitis: C2CD4B, EGR3, FOSB, IRF1, and JUNB [17,19,20,21].