To further substantiate our findings, we also carried out a meta-analysis of the published literature to quantitatively summarize the impact of ABCB1 c.3435C>T, c.2677G>T/A, c.1236C>T, and ABCG2 c.421A>C on imatinib plasma Ctrough in CML and GIST. Here, ABCG2 is linked to gastrointestinal stromal tumor.