PCLAF and hepatocellular carcinoma: PCLAF tv1 was positively stained in 81.0% (34/42) of HBV-HCC specimens and 53.3% (16/30) of non-virus HCC specimens using immunohistochemistry (IHC) (p < 0.05; Figure 1c,d), providing evidence that PCLAF tv1 was significantly overexpressed in HBV-HCC compared to non-virus HCC.