For instance, endothelial TRPC1 supported VEGF-induced angiogenic sprouting of intersegmental vessels in zebrafish larvae [212], maintained the plateau phase of VEGF-induced extracellular Ca2+ entry in MAECs [213], induced wound healing in HMECs [214], and promoted vascular regrowth and recovery of myocardial function in a mouse model of acute myocardial infarction [215]. The gene discussed is VEGFA; the disease is acute myocardial infarction.