More than 90% of diagnosed BCs are associated with the mutation of specific genes, such as breast cancer genes 1 and 2 (BRCA1 and BRCA2), TP53, phosphatase and tensin homolog (PTEN), serine/threonine kinase 11 (STK11), ataxia-telangiectasia mutated (ATM), BRCA1 interacting protein 1 (BRIP1) or the partner and localizer of BRCA2 (PALB2), etc. [11]. Here, PTEN is linked to cancer.