Similarly to AP, lower levels of mHLA-DR expression correlated with length of hospital stay [140], SOFA score [153], and serum clinical biochemical parameters including D-dimer, lactate dehydrogenase, CRP, procalcitonin, ferritin, IL-6, IL-10, granulocyte colony-stimulating factor, chemokine C-X-C motif ligand 10, chemokine C-C motif ligand 2 (CCL2), and IFN-γ levels [135,136,137,144,147,153,163]. This evidence concerns the gene CRP and alkaline phosphatase measurement.