All up-regulated (NCAPG, MKI67, CCNA2, CCNB1, TPX2) and down-regulated (CDK1, CCNB2, AURKA, UBE2C, BUB1B, CENPF, RRM2) genes were expressed significantly higher in aggressive PCa (Gleason score > 7) tissues. Here, BUB1B is linked to posterior cortical atrophy.