To this aim, we analyzed two additional RNA sequencing datasets (NCBI GEO: GSE203173 and dbGaP: phs000747) obtained from in vitro derived MNs carrying the H517Q FUS mutation and from sporadic ALS post-mortem tissues (ventral horns of the lumbar spinal cords), respectively [62,63]. This evidence concerns the gene FUS and amyotrophic lateral sclerosis.