In addition, Fang et al. described that SLE patients had higher methylation and thus lower expression in the histone deacetylases 6 (HDAC6) promoter than healthy controls; decreased HDAC6 levels could result in increased histone acetylation and high immune-related gene expression; therefore, the authors suggested that may be related to SLE susceptibility [23] (Table 1). The gene discussed is HDAC6; the disease is systemic lupus erythematosus.