AFP and hepatocellular carcinoma: Using these suggested ratio cutoffs revealed a 100% detection rate of HCC in AFP-negative HCC patients (12/39) if using hsa-miR-21-5p/hsa-miR-199a-5p or a 91.6% detection rate of HCC in AFP-negative HCC cases if using hsa-miR-155-5p/hsa-miR-199a-5p ratio as screening molecular markers, which was confirmed with CT scan.