Compared with WT mice, collagen accumulation was suppressed in Ccl3−/− and Ccr5−/− mice but not in Ccr1−/− mice, suggesting that locally produced CCL3 interacts with CCR5 and participates in the mobilization of bone marrow-derived macrophages and fibrocytes, the main producers of TGF-β1 by BLM, and in the subsequent development of PF [44]. Here, TGFB1 is linked to pemphigus foliaceus.