To further verify whether CpG-ODN alleviates Th2/Th17-type inflammatory responses in smoke-related asthma by inhibiting the TSLP-DC pathway, consequently, the levels of TSLP, anti-HDM IgE, proinflammatory or anti-inflammatory cytokines, and Th1/Th2/Th17-cytokines were detected in the smoke-related asthma model induced by adoptive transfer of BMDCs. Here, IGHE is linked to asthma.