Wang et al., by constructing a Con A-induced acute immune liver injury model in mice, found that PEITC could reduce NLRP3 production and casp1 and GSDMD cleavage in the liver of ALI-suffering mice and directly interact with the cysteine at position 191 of GSDMD to inhibit hepatocyte pyroptosis, thereby exerting a significant hepatoprotective effect [172]. Here, GSDMD is linked to acute respiratory distress syndrome.