Therefore, the alleles encoding the amino acid sequences in HLA directly affect the susceptibility to certain diseases, e.g., H1N1 influenza (HLA-A*11, DRB1*10, HLA-B*35) [10], dengue infection (HLA-B*51, HLA-B*52, HLA-B*46) [11], AIDS (HLA-B*52) [12], etc. [13,14]. Here, HLA-B is linked to AIDS.