This study observed the GSTT1(rs17856199), GSTM1(rs366631), GSTP1(rs1695), KCNQ1(rs2237892), ACE(rs4646994), and TCF7L2(rs12255372; rs7903146; rs7901695) loci to be associated with T2DM in a north Indian population of Jat Sikhs. Here, TCF7L2 is linked to type 2 diabetes mellitus.