MG is an immunologic disorder in which acetylcholine (AChR) or other receptors on the post-synaptic membrane, such as muscle-specific kinase (MuSK), titin, ryanodine receptors, etc. are degraded by immunological mechanisms such as complement-mediated receptor degradation by circulating antibodies, accelerated endocytosis, or functional blockade of the post-synaptic receptors. Here, MUSK is linked to myasthenia gravis.