Particularly, alterations of interleukin-6 (IL-6), interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) as well as interferon-γ (INF- α) have been implicated in impaired processes of synaptic plasticity and neuroinflammation paths, underlying functional and cognitive anomalies related to PTSD [12]. The gene discussed is IL1B; the disease is post-traumatic stress disorder.