A deeper understanding of the effects of alcohol on BC parameters could have been achieved with this study if the available data included laboratory measurements of serum biomarkers and metabolic active products of adipose tissue lipocytes: growth factors (FGF-21 and FGF-23 [83], VEGF [84], TGF-β [85]), lipid acids [84], adipokines (adiponectin, leptin), cytokines (IL-1β, IL-8, IL-10, IL-18, IL-17D, MCP-1), prostaglandins, extracellular matrix (collagen II-VI, thrombospondin-1) [85], and inhibitors of proteases (cystatin C [86], TIMP-1 [87]). The gene discussed is IL18; the disease is breast cancer.