In a study from the Clinical Breast Care Project (CBCP), in which gene expression profiling was performed from tumor epithelial cells of HR+/HER2− breast tumors from 57 Black and 181 White women, 10 genes were differentially expressed between populations, with the highest-fold changes detected not for CRYBB2 and PSPH but for the pseudogenes CRYBB2P1 and PSPHP1 [18]. The gene discussed is PSPH; the disease is neoplasm.