OAS1 and foot and mouth disease: An investigation into Taiwanese children (Controls n = 163; positive patients n = 333) that suffered from hand, foot and mouth disease, human enterovirus, and coxsackie virus revealed that children with the homozygous “GG” genotype of rs10774671 (OAS-1; G > A) were susceptible to coxsackie virus infection, while children that suffered with hand, foot and mouth disease, and had a “AA” and “AG” genotype, were more prone to develop encephalitis [61].