AMBP and Fabry disease: Considering the renal involvement in Fabry disease, apart from classical investigations such as albuminuria, proteinuria, β2-microglobulin, urinary microscopy, creatinine, serum urea, uric acid, GFR, ultrasound and kidney biopsy, one should also take in consideration potential new biomarkers such as urinary Gb3, uromodulin, prostaglandin H2 D-Isomerase and bikunin [28].