Biological investigations revealed the presence of an important nitrogen retention (urea 270 mg/dL, creatinine 16 mg/dL and a GFR of 4 mL/min/1.73 m2) associated with severe hypo regenerative normochromic normocytic anemia (Hb 6.8 g/dL, Ht 20.5%, MCV 80.8 μ3, MHC 29.7 pg%, MCHC 36.8%, Reticulocytes 20‰), with high serum iron 125γ%, and ferritin 611 ng/mL, metabolic acidosis (13 mmol/L), hypocalcemia (0.4 mmol/L), hyperphosphatemia (6.64 g/L) and high alkaline phosphatase—1897 IU/L. This evidence concerns the gene GSTM1 and anemia (phenotype).