So far, HGMD Professional 2018.4 (http://www.hgmd.cf.ac.uk/ac/gene.php?gene=DYM/, accessed on 30 August 2022) has a registry of 44 pathogenic variants (missense/non-sense (18 variants), splicing substitutions (11 variants), deletions (11 variants), and insertions/duplications (4 variants)) in DYM, causing DMC, SMC1, intellectual disability, and other dysmorphic phenotypes (Table S2). Here, DYM is linked to Intellectual disability.