CHST14 and Ehlers-Danlos syndrome: They proposed to unify the D4ST1-related syndromes, the novel EDS and the adducted thumb–clubfoot syndrome, as ‘‘musculocontractural EDS’’ [143], which was adopted in the International Classification of Ehlers–Danlos Syndromes in 2017 as EDS musculocontractural type 1 [144,145].