Finally, in the present study, we did not find significant differences in TILs subpopulation according to age, tumor site, EOR, MGMT promoter methylation, proliferation index, 1p/19q c-deletion, TP53, IDH1/2 status, and risk of recurrence, which suggests that these prognostic factors may have an impact on patient prognosis in different ways. This evidence concerns the gene IDH1 and neoplasm.