Meanwhile, neutrophils have a binary role, eithersuppressing tumor progression in the early stages or promoting tumor growth via release of several molecules, such as matrix metalloprotease (MMP) −9 and vascular endothelial growth factor (VEGF), which further promote alterationinextracellular matrix consistency, invasion of tumor cells in the neighbor tissues, and neoangiogenesis [12]. Here, VEGFA is linked to neoplasm.