For this purpose, 103 CD patients and 100 PsO patients of Greek origin were genotyped for both variants using the PCR-RFLP method, creating a de novo restriction site for the SacI endonuclease regarding the MIR146A rs2910164 SNP genotyping, whilst the Tsp45I enzyme was utilized for the MIR155 rs767649 PCR-RFLP analysis. This evidence concerns the gene ADCY10 and Cowden disease.