Genetic variants in other genes encoding for splicing factors (PRPF3, PRPF4, PRPF6, PRPF8, RP9, snRNP200) can also lead to autosomal dominant RP, but PRPF31 variants are the most frequent cause of splicing-factor-related RP [19]. Here, PRPF31 is linked to retinitis pigmentosa 1.