This is clearly exemplified by one study (n = 7 RP + 3 NPC) which reported a 29–42% increase in PRPF31 expression in NPCs compared to RP individuals [35], and another study (n = 8 RP + 7 NPC) demonstrated a significant difference (p < 0.001) in mRNA copy number between the two groups [34]. Here, PRPF31 is linked to nasopharyngeal carcinoma.