CHST14 and Ehlers-Danlos syndrome, musculocontractural type: Musculocontractural EDS (mcEDS) is a rare subtype of EDS caused by mutations in the genes encoding carbohydrate sulfotransferase 14 (mcEDS-CHST14; MIM#601776) or dermatan sulfate epimerase (mcEDS-DSE; MIM#615539) (Figure 1) [1,3,4,5,6,7,8].