The discovery of the deleterious effect of ELMO1 alterations in CD may provide a link in association to many gastrointestinal tumors, mainly esophageal and gastric cancer, which feature alterations of ELMO1 in up to 8%, and this gene has been proposed as a diagnostic or prognostic biomarker [90,91,107,110]. The gene discussed is ELMO1; the disease is gastric cancer.