PALB2 and cancer: FANCI is not currently included among the 733 cancer-driving genes in the Cancer Gene Census [119], but a number of other genes involved in the FA pathway, such as BRCA1 (FANCS), BRCA2 (FANCD1), BRIP1 (FANCJ), FANCA, FANCC, FANCD2, PALB2 (FANCN), and RAD51C (FANCO), are implicated as cancer drivers in this census.