ANK3 and schizophrenia: Schizophrenia-associated loci encoding proteins involved in inhibitory neurotransmission include GABAB receptor components GABBR1 and GABBR2 and loci linked to proteins that mediate GABA receptor turnover such as ankyrin-G (ANK3), which stabilises somatodendritic GABAergic synapses and, in an rs41283526 variant could be protective against schizophrenia.