KDR and schizophrenia: Some findings also indicate a decrease in the expression of genes related to growth factor pathways in the PFC of patients with schizophrenia, i.e., vascular endothelial growth factor receptor 2 (VEGFR2/KDR) [67]; Sprouty 2, a regulator of growth factor signalling; and brain-derived neurotrophic factor (BDNF) [68].