EXOSC9 and Cerebellar atrophy: Based on the preliminary diagnosis of cerebral and cerebellar atrophy on brain MRI, only three genes causative of AR forms of white matter diseases were lying within the observed 24 Mb regions of homozygosity, including EXOSC9 (OMIM *606180), SPATA5 (OMIM *613940) and MFSD8 (OMIM *611124).