Therefore, according to the presenting phenotype, patients were originally clustered into the six different NCL subtypes [4], consisting of congenital (CLN10), infantile (CLN1), late infantile (CLN2), variant late infantile (CLN5, CLN6, CLN7 and CLN8), juvenile (CLN3) and adult (CLN4) NCL. The gene discussed is DNAJC5; the disease is neuronal ceroid lipofuscinosis.